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Enzo Life Sciences CGP 74514A (5mg)

Supplier: Enzo Life Sciences ALX270391M005
Cell permeable, potent and selective inhibitor of CDK1/cyclin B (IC50=25nM). Reported to affect the activities of other kinases only at much higher concentrations: PKCα (IC50=6.1µM), PKA (IC50=125µM) and EGFR (IC50>10µM). Induces mitochondrial damage and apoptosis in several human leukemia cell lines (>3µM). Alternative name: N-(cis-2-Aminocyclohexyl)-N-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
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