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Cayman Chemical CGRP (8-37) (mouse, rat) (trifluoroacetate salt), Purity: ≥95%, 5 mg
SDP

Catalog No. 502913348
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A CGRP receptor antagonist; selectively binds to heterotrimeric complexes of CRLR and RAMP1 or RAMP3 over a complex of CLCR and RAMP2 (IC50s = 1, 6.2, and 219 nM, respectively); prevents CGRP-induced increases in heart rate and decreases in blood pressure in transgenic mice expressing rat CRLR in smooth muscle-containing tissues and sympathetic ganglia at 2 µmol/kg; inhibits p-phenylquinone-induced writhing (ED50 = 6 µg/animal) and decreases body temperature in mice

Catalog No. 50-291-3348 Supplier Cayman Chemical Supplier No. 356455 MG
May include imposed supplier surcharges.
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A CGRP receptor antagonist; selectively binds to heterotrimeric complexes of CRLR and RAMP1 or RAMP3 over a complex of CLCR and RAMP2 (IC50s = 1, 6.2, and 219 nM, respectively); prevents CGRP-induced increases in heart rate and decreases in blood pressure in transgenic mice expressing rat CRLR in smooth muscle-containing tissues and sympathetic ganglia at 2 µmol/kg; inhibits p-phenylquinone-induced writhing (ED50 = 6 µg/animal) and decreases body temperature in mice

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