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STEMCELL Technologies CH223191, Size: 10 mg
Supplier: STEMCELL Technologies 72732
CH223191 is a potent and specific antagonist of the aryl hydrocarbon receptor (AhR) that blocks activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; IC₅₀ = 0.03 µM; Kim et al.). It prevents the induction of cytochrome P450 1A1 by TCDD in HepG2 cells and in livers of mice (Kim et al.).MAINTENANCE AND SELF-RENEWAL· Induces expansion of human CD34+ hematopoietic stem and progenitor cells in culture (Boitano et al.).
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