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Apexbio Technology LLC Chidamide(Synonyms: Epidaza, HBI-8000, CS055, Tucidinostat, Entinostat analog, Chidamide (CS055)), 10mM (in 1mL DMSO), CAS: 743420-02-2.
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Supplier:  Apexbio Technology LLC B59165.1

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Chidamide (CAS 743420-02-2) is a benzamide-based histone deacetylase (HDAC) inhibitor that targets enzymes responsible for the reversible acetylation of lysine residues on histone tails By modulating HDAC activity Chidamide promotes chromatin remodeling influencing transcription factor access and subsequent gene transcription In vitro studies on human leukemia cell lines and primary myeloid leukemia cells indicate that Chidamide induces cell cycle arrest at the G1 phase differentiation and apoptosis via ROS-dependent mechanisms Therefore Chidamide shows considerable potential in research focused on hematologic malignancies and cancer therapy

Catalog No. 50-000-60043


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