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Abcam CHIR99021, GSK3 inhibitor, 5MG
Supplier: Abcam AB1208905MG

MW 465.3 Da, Purity >98%. Potent, highly selective aminopyrimidine GSK3 inhibitor (IC₅₀ values are 6.7 and 10 nM at GSK3β and GSK3α, respectively). Exhibits >500-fold selectivity for GSK3 against 20 closely related protein kinases and >800-fold selectivity for 23 additional enzymes and 22 receptors. Promotes self-renewal of mouse and human ESC due to β-catenin and c-Myc protein level stabilization. Commonly used in multiple stages of organoid generation.
The product is subject to the following: Abcam Restricted Use Statement
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