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Medchemexpress LLC Chitin, from crab carapace (powder), biomedical research grade | 1398-61-4 | 100 G
Supplier: Medchemexpress LLC HY126389100G
Chitin, from crab carapace is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. It is found in the exoskeleton of crabs. This product inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. It exerts antifungal and anti-inflammatory effects and can be used in the research of gastric ulcer and candidiasis.
- Shows antifungal activity against 20 clinical isolates of Candida spp.
- Significantly reduces gastric ulcer index and inhibits NF-κB p65 expression in the Wistar rat model.
- Results in decreased necrotic cells and fat degeneration, and increased normal cells in gastric mucosa.
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