Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Chlorambucil 305-03-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B37165.1
Chlorambucil (CAS 305-03-3) is an alkylating chemotherapeutic agent belonging to the nitrogen mustard class Its primary mechanism involves forming crosslinks within DNA strands both intra- and inter-strand crosslinks resulting in impaired DNA replication and transcription ultimately inducing cell death In vitro studies showed that chlorambucil potently inhibits human microvascular endothelial cells (IC 0 53 M) and exhibits cytotoxic activities against glioma cell lines such as SF767 (IC 114 M) and U87-MG (IC 96 M) Chlorambucil is widely used in research settings to investigate cell apoptosis DNA damage and lymphoid malignancies like chronic lymphocytic leukemia (CLL)
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?