Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Chloramphenicol | 56-75-7 | 100.0% | 250 MG
Supplier: Medchemexpress LLC 250MGHYB0239R
Chloramphenicol is an orally active, potent, and broad-spectrum antibiotic with antibacterial activity. It represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. It also suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, leading to decreased VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research.
- Inhibits HIF-1α pathway in NSCLC cells
- Induces autophagy in NSCLC cells
- Inhibits bacterial and mitochondrial protein synthesis
- Induces matrix metalloproteinase (MMP)-13 expression
- Activates JNK and PI-3K/Akt signaling
- Inhibits peptide bond formation by acting on the 50S subunit of bacterial 70S ribosomes
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?