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Medchemexpress LLC Chloramphenicol succinate sodium | 982-57-0 | 1 ML
Supplier: Medchemexpress LLC HYN7114A10MM/1ML
Chloramphenicol succinate sodium is a prodrug of Chloramphenicol, acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. It also serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH). This compound has shown significant inhibitory effects on colitis and is used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis, and inflammatory bowel disease. It is slowly oxidized to Chloramphenicol by human bone marrow monocytes and mitochondria from liver and kidney.
- Molecular weight: 445.18
- Formula: C15H15Cl2N2NaO8
- Appearance: Solid, white to light yellow
- Purity: 97.17% (as per data sheet)
- Soluble in DMSO (125 mg/mL) and H2O (50 mg/mL)
- Alleviates DSS-induced colitis in mice
- Enhances gut barrier integrity via increased tight junction protein expression
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