Alfa Aesar™ Chloromethyl pivalate, 97%

Manufacturer: Alfa Aesar™ A1196722

Quantity 100g

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Catalog No. AAA1196722

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    Chemical Identifiers

    CAS 18997-19-8
    Molecular Formula C6H11ClO2
    Linear Formula (CH3)3CCO2CH2Cl
    Formula Weight 150.60g/mol
    MDL Number MFCD00000884
    UN Number UN2924
    Beilstein 1560838
    Synonym Chloromethyl trimethylacetate; Pivaloyloxymethyl chloride
    Chemical Name or Material Chloromethyl pivalate

    Specifications

    Boiling Point 146° to 148°C
    Quantity 100g
    Flash Point 40°C (104°F)
    CAS 18997-19-8
    Molecular Formula C6H11ClO2
    Linear Formula (CH3)3CCO2CH2Cl
    Formula Weight 150.60g/mol
    MDL Number MFCD00000884
    UN Number UN2924
    Beilstein 1560838
    Synonym Chloromethyl trimethylacetate; Pivaloyloxymethyl chloride
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H314-H318-H226
    Causes severe skin burns and eye damage.
    Causes serious eye damage.
    Flammable liquid and vapor.
    Health Hazard 3 GHS P Statement
    P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
    Keep away from heat/sparks/open flames/hot surfaces.
    - No smoking.
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
    Continue rinsing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    DOT Information Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
    TSCA TSCA
    Chemical Name or Material Chloromethyl pivalate
    Assay 97%

    Description

    Applications
    Chloromethyl pivalate acts as an intermediate in the synthesis of active pharmaceutical ingredients. It is also involved in the acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine. It serves as a protecting reagent used for the N-protection of amines. It is also employed in the preparation of pivaloyloxy methyl ester of ofloxacin as a prodrug. Further, it is used to prepare sulbactam pivoxil by reaction with sodium salt of sulbactam. In addition to this, it is used as a reagent during the synthesis of an isoindoline-annulated and continuous-flow organic synthesis.

    Solubility
    Miscible with most organic solvents. Immiscible with water.

    Notes
    Incompatible with strong oxidizing agents.

    GHS H Statement
    H314-H318-H226
    Causes severe skin burns and eye damage.
    Causes serious eye damage.
    Flammable liquid and vapor.

    GHS P Statement
    P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
    Keep away from heat/sparks/open flames/hot surfaces.
    - No smoking.
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
    Continue rinsing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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