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Chloromethyl pivalate, 97%, Thermo Scientific™

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Quantity:
25g
100g
18997-19-8
C6H11ClO2
150.60
MFCD00000884
GGRHYQCXXYLUTL-UHFFFAOYSA-N
chloromethyl pivalate, propanoic acid, 2,2-dimethyl-, chloromethyl ester, pivalic acid chloromethyl ester, pivaloyloxymethyl chloride, pivaloylmethyl chloride, chloromethyl trimethylacetate, 2,2-dimethylpropionic acid chloromethyl ester, chioromethyl pivalate, chloromethyl pivaloate, chloro-methyl pivalate
87885
chloromethyl 2,2-dimethylpropanoate
CC(C)(C)C(=O)OCCl
18997-19-8
C6H11ClO2
150.60
MFCD00000884
GGRHYQCXXYLUTL-UHFFFAOYSA-N
chloromethyl pivalate, propanoic acid, 2,2-dimethyl-, chloromethyl ester, pivalic acid chloromethyl ester, pivaloyloxymethyl chloride, pivaloylmethyl chloride, chloromethyl trimethylacetate, 2,2-dimethylpropionic acid chloromethyl ester, chioromethyl pivalate, chloromethyl pivaloate, chloro-methyl pivalate
87885
chloromethyl 2,2-dimethylpropanoate
CC(C)(C)C(=O)OCCl

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Chloromethyl pivalate acts as an intermediate in the synthesis of active pharmaceutical ingredients. It is also involved in the acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine. It serves as a protecting reagent used for the N-protection of amines. It is also employed in the preparation of pivaloyloxy methyl ester of ofloxacin as a prodrug. Further, it is used to prepare sulbactam pivoxil by reaction with sodium salt of sulbactam. In addition to this, it is used as a reagent during the synthesis of an isoindoline-annulated and continuous-flow organic synthesis.

Solubility
Miscible with most organic solvents. Immiscible with water.

Notes
Incompatible with strong oxidizing agents.
Density 1.045
Boiling Point 146°C to 148°C
Flash Point 40°C (104°F)
Linear Formula (CH3)3CCO2CH2Cl
UN Number UN2924
Beilstein 1560838
Refractive Index 1.417
Quantity 100g
Solubility Information Miscible with most organic solvents. Immiscible with water.
Formula Weight 150.6
Percent Purity 97%
Chemical Name or Material Chloromethyl pivalate
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GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.

P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

H226-H302-H312-H314-H332-H335

DOTInformation : Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.

EINECSNumber : 242-735-1

TSCA : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only