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Cayman Chemical ChlorphensIn Carbamate 100mg

Supplier: Cayman Chemical 39252100 MG

An inhibitor of Src MET and FMS kinases (IC50s 0.12 0.14 and 0.76 nM respectively) inhibits the proliferation of MKN45 and SNU-5 human gastric cancer cells (IC50s 0.2 and 0.17 nM respectively) as well as Ba/F3 pro-B cells expressing TEL-CSF1R (IC50s 19.3 nM) inhibits cell migration of HCC827 cells at 100 nM inhibits tumor growth in a MKN45 mouse xenograft model at 10 and 30 mg/kg inhibits phosphorylation of MET at Tyr1234 and Tyr1349 in the same model at 10 mg/kg
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