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Cayman Chemical Chlorzoxazon-d3 1mg

Supplier: Cayman Chemical 342371 MG

An agonist of FPR1 and FPR2 induces calcium flux in CHO cells expressing human FPR2 Ga15 and aequorin (EC50 0.044 UM) and in CHO-K1 cells expressing either human FPR1 human FPR2 mouse Fpr1 or mouse Fpr2 Ga16 and aequorin in a concentration-dependent manner inhibits fMLP- or IL-8-induced neutrophil migration (IC50s 0.64 and 0.24 UM respectively) reduces PGE2- and LTB4-induced ear swelling in mice at 50 mg/kg
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