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Medchemexpress LLC CHMFL-PI4K-127 | 2377604-81-2 | C18H15ClN4O3S | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1505985MG

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CHMFL-PI4K-127 (compound 15g) is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor, with an IC50 of 0.9 nM. It exhibits potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM, and shows antimalaria efficacy. This product is for research use only and not for sale to patients.

  • Potent and highly selective PfPI4K inhibitor
  • Orally active
  • Exhibits potent activity against 3D7 Plasmodium falciparum
  • Shows antimalaria efficacy
  • Demonstrates high selectivity against PfPI4K over human lipid and protein kinases
  • Effective against drug-resistant strains of P. falciparum
  • Significant in vivo antimalarial activities in rodent models
  • Provides full protection and cure at 1 mg/kg in liver stage infection

Catalog No. 50-003-75285


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