Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Genscript Corporation CHO-K1/5-HT2B Stable Cell Line
Supplier: Genscript Corporation M00249
5-Hydroxytryptamine (5-HT also commonly known as serotonin) is synthesized in enterochromaffin cells in the intestine and in serotonergic nerve terminals In the periphery 5-HT mediates gastrointestinal motility platelet aggregation and contraction of blood vessels Many functions of the central nervous system are influenced by 5-HT including sleep motor activity sensory perception arousal and appetite A family of 12 GPCRs and one ion channel mediate the biological effects of 5-HT (Hoyer et al 1994) 5-HT2B which couples to Gq/11 is expressed in embryonic and adult cardiovascular tissues gut and brain from the rat mouse and human species 5-HT2B receptors are responsible for many cardiovascular and central nervous system functions such as blood vessel contraction platelet shape changes neuronal sensitization to tactile stimuli and mediation of the hallucinogenic effects of phenylisopropylamin hallucinogens It has also been shown to be required for heart develo
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?