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Genscript Corporation CHO-K1/CASR Stable Cell Line
Supplier: Genscript Corporation M00434
CASR is a calcium-sensing receptor and plays an important role in regulating PTH secretion It is expressed in many different tissues such as parathyroid pancreatic islet and insulinoma cells breast gastrinoma cells pituitary keratinocytes and human colon epithelial cells CASR Inhibits PTH secretion and parathyroid cellular proliferation in parathyroid glands or cells and also inhibits proliferation of colonic crypt cells Besides it can stimulate PTHrP secretion in prostate cell line and stimulate calcitonin secretion from thyroidal C-cells
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