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Genscript Corporation CHO-K1/H3/G15 Stable Cell Lin
Supplier: Genscript Corporation M00331
The histamine receptor H3 is a G sub i /sub -coupled GPCR expressed in the thalamus caudate nucleus putamen cerebellum amygdala substantia nigra hippocampus hypothalamus and cerebral cortex Activation of H3 receptor in human nasal mucosa inhibits sympathetic vasoconstriction Expression of human H3 receptor splice variants in CHO cells shows that a deletion in the 2nd transmembrane domain alters ligand binding and deletions in the 3rd intracellular loop result in signal transduction being abolished
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