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Genscript Corporation CHO-K1/SST1/Gqi5 Stable Cell L
Supplier: Genscript Corporation M00473
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner SST1 receptor is a Gi/Go-coupled GPCR which is expressed in pancreatic islets pituitary Cerebellum (Purkinje cells) frontal cortex (pyramidal cells) hippocampus (CA1-4 subfields and some granule cells of the dentate gyrus) It inhibits cAMP accumulation and stimulates tyrosine phosphatase activity it also can antiproliferation br GenScript s SST1-expressing stable cell line was made in CHO-K1/Gqi5 host cell and optimized for calcium assays
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