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Eurofins Discoverx PathHunter CHO-K1 cyno MRGPRX2 β-Arrestin Cell Line, 2 vials. (93-1134C2)
Supplier: Eurofins Discoverx 931134C2
The PathHunter cyno MRGPRX2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PAMP-20) based activation of cyno MRGPRX2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno MRGPRX2 and EA-tagged β-Arrestin-2. Activation of cyno MRGPRX2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cynomolgus monkey version of the protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
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