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Eurofins Discoverx PathHunter CHO-K1 FXR Protein Interaction Cell Line, 2 vials. (93-0443C2)

Supplier:  Eurofins Discoverx 930443C2

Encompass

The PathHunter FXR Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. cholic acids) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. The included cell line overexpresses ProLink-tagged FXR (farnesoid X receptor) NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of FXR, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.

Catalog No. 50-200-0553


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