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Eurofins Discoverx PathHunter CHO-K1 GR Nuclear Translocation Cell Line, 2 vials. (93-0002C2)
Supplier: Eurofins Discoverx 930002C2
The PathHunter GR Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. dexamethasone) based NHR activation via detection of resulting GR (glucocorticoid receptor) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged GR NHR and nuclear localized EA. Upon activation of GR, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
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