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Eurofins Discoverx cAMP Hunter CHO-K1 PPYR1 (NPY4R) Gi Cell Line, 2 vials. (95-0087C2)
Supplier: Eurofins Discoverx 950087C2
The cAMP Hunter PPYR1 (NPY4R) Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. pancreatic polypeptide, peptide YY) based activation of PPYR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PPYR1, a naturally Gi/Go coupled GPCR. Upon activation of PPYR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
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