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Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY11241510MG

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Lith-O-Asp is a sialyltransferase (ST) inhibitor with IC50 values ranging from 12-37 μM. It has been shown to decrease the activity of both α-2,3- and α-2,6-sialyltransferases, thereby inhibiting the transfer of sialic acids to targeted glycoproteins. Research indicates that Lith-O-Asp may suppress cancer angiogenesis and metastasis pathways, as demonstrated by fewer lung metastases in treated mice compared to controls.

  • Sialyltransferase (ST) inhibitor.
  • Inhibits the activities of ST3Gal I, ST3Gal III, and ST6GalI.
  • Decreases expression of cell surface α-2,3- and α-2,6-sialylated antigens.
  • Suppresses cancer angiogenesis and metastasis pathways.

Catalog No. 50-004-36434


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