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Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11241550MG

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Lith-O-Asp is a sialyltransferase (ST) inhibitor with IC50s ranging from 12-37 μM. It has been shown to decrease the activity of both a-2,3- and a-2,6-sialyltransferases, inhibiting the transfer of sialic acids to targeted glycoproteins. Research indicates that Lith-O-Asp can suppress FAK/paxillin signaling, as well as cancer angiogenesis and metastasis pathways. It has demonstrated an ability to reduce lung metastases in animal models.

  • Sialyltransferase (ST) inhibitor
  • IC50s of 12-37 μM
  • Suppresses FAK/paxillin signaling
  • Inhibits cancer angiogenesis and metastasis pathways
  • Decreases activity of a-2,3- and a-2,6-sialyltransferases
  • Inhibits transfer of sialic acids to targeted glycoproteins
  • Reduces lung metastases in vivo

Catalog No. 50-004-36435


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