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Cayman Chemical Cholesteryl ArachIdate 50mg

Supplier: Cayman Chemical 2646550 MG

An orally bioavailable Bcl-xL inhibitor selectively binds Bcl-xL over Bcl-2 Mcl-1 and Bcl-W (Kis in vitro (EC50s 6 and 5000 nM respectively) inhibits tumor growth in a MOLT-4 mouse xenograft model at 25 mg/kg inhibits tumor growth and increases the antitumor activity of docetaxel in MDA-MB-231 LC3 metastatic breast cancer and NCI-H1650 non-small cell lung cancer mouse xenograft models at 25 mg/kg
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