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Cayman Chemical Cholesteryl ArachIdonate 10mg

Supplier: Cayman Chemical 2259510 MG

An alkaloid with diverse biological activities active against several strains of E histolytica amoebae (IC50s 0 73-10 22 g/ml) inhibits NF-KB signaling induced by TNF-a or IL-1B (IC50s 2 and 4 2 M respectively in a cell-basedBlactamase reporter assay) increases caspase-3/7 activity in ME180 cells (EC50 1 1 M) cytotoxic to HeLa cells reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s 0 46 and 0 5 M respectively) induces emesis in ferrets at 5 mg/kg an effect that can be prevented by ondansetron
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