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Cayman Chemical Cholesteryl Butyrate 5g

Supplier: Cayman Chemical 409505 G

A STING agonist binds to STING (Kd 23 UM) induces the production of IFN-B IL-6 and CXCL10 in THP-1 cells at 10 25 and 50 UM induces phosphorylation of IRF3 and TBK1 in THP-1 cells at 50 UM reduces tumor volume in an MC-38 murine carcinoma model and induces tumor regression in a CT26 murine colorectal carcinoma model at 15 and 30 mg/kg prevents tumor cell re-challenge-induced tumor formation in a CT26 murine carcinoma model reduces tumor volume and increases the number of activated CD8 T cells and NK cells in a 4T1 murine mammary carcinoma model at 20 mg/kg
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