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Cayman Chemical Cholesteryl Docosapentaenoate
SDP

Supplier:  Cayman Chemical 227181 MG

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A BTK inhibitor (Kis 0 91 1 6 1 3 12 6 and 3 4 nM for wild-type BTK BTKC481S BTKC481R BTKT474I and BTKT474M respectively) selective for BTK over a panel of 287 additional kinases at 1 UM inhibits anti-IgM antibody-induced BTK phosphorylation in B cells (IC50 3 1 nM) as well as anti-IgM- or CD40L-induced proliferation of B cells (IC50s 1 2 and 1 4 nM respectively) reduces ankle thickness and cartilage damage in a rat model of collagen-induced arthritis

Catalog No. 50-299-5422


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