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Cayman Chemical Cholesteryl LIgnocerate 25mg

Supplier: Cayman Chemical 2647025 MG

An inhibitor of Gal-1 decreases lactose binding to Gal-1 (Kds 290 and 100 M in the presence and absence of compound respectively) cytotoxic against a cancer cell panel with IC50 values that directly correlate to Gal-1 mRNA expression inhibits proliferation of HUVECs (IC50 2 M) and reduces HUVEC migration in a wound healing assay reduces tumor growth in the MA148 ovarian mouse xenograft model and the B16 murine melanoma syngeneic model via decreases in tumor microvessel density and induction of apoptosis (2.4 and 10 mg/kg)
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