Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Cholic acid 7-sulfate | 60320-05-0 | 99.9% | 25 MG
Supplier: Medchemexpress LLC 25MGHY126855
Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). It functions as a gut-restricted TGR5 agonist, binding to TGR5 on enteroendocrine L cells to induce GLP-1 secretion and improve glucose tolerance in a TGR5-dependent manner. Additionally, it acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells (MAIT) and affecting MAIT cell development and function. This compound is primarily used in the research of diabetes and MAIT cell-related immune regulation.
- Selective agonist targeting TGR5 (EC50=0.17 μM)
- Ligand for MHC class I-related protein (MR1)
- Induces GLP-1 secretion
- Improves glucose tolerance
- Promotes MAIT cell survival
- Used in diabetes research
- Used in MAIT cell-related immune regulation
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?