Cholic acid sodium salt, Thermo Scientific Chemicals

Description

Biochemical solubilizing agent

Cholic acid sodium salt is a bio-surfactant which can be used as a reducing reagent in aqueous solution. It is also used as a non-denaturing detergent used for extraction of membrane proteins. Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cholic acid sodium salt is a bio-surfactant which can be used as a reducing reagent in aqueous solution. It is also used as a non-denaturing detergent used for extraction of membrane proteins. Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

Solubility
It is soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 206986-87-0
• Molecular Formula: C24H39NaO5
• Molecular Weight (g/mol): 430.56
• MDL Number: MFCD00064138 MFCD00003672
• InChI Key: NRHMKIHPTBHXPF-TUJRSCDTSA-M
• Synonym: sodium cholate hydrate, cholalic acid sodium salt, c24h39o5.na.h2o, sodium cholate hydrate, bioxtra, sodium cholate hydrate dried material, nt, sodium cholate hydrate, from ox and/or sheep bile, 3, a,7, a,12, a-trihydroxy-5, a-cholan-24-oic acid sodium salt, sodium cholate hydrate, suitable for cell culture, bioreagent, 4r-4-1s,2s,7s,11s,16s,5r,9r,10r,14r,15r-5,9,16-trihydroxy-2,15-dimethylte tracyclo 8.7.0.0<2,7>.0<11,15> heptadec-14-yl pentanoic acid, sodium salt, hyd rate, sodium cholate hydrate, pharmagrade, manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
• PubChem CID: 23679061
• IUPAC Name: sodium (4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoate
• SMILES: [Na+].[H][C@@]12CC[C@H]([C@H](C)CCC([O-])=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C

• Color: White
• Quantity: 25 g
• Beilstein: 3582354
• Merck Index: 14,2203
• Solubility Information: It is soluble in water.
• Formula Weight: 430.6
• Physical Form: Powder
• Chemical Name or Material: Cholic acid sodium salt

Safety and Handling

TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only