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Cayman Chemical CholSTRl 11 14EIcosadIeno 50mg

Supplier: Cayman Chemical 2646750 MG

A DYRK1A inhibitor (Ki 180 nM IC50 240 nM) selective for DYRK1A over MAOA and B (100 M) inhibits DYRK1A phosphorylation of tau in COS-7 cells expressing EGFP-DYRK1A and EGFP-tau in a concentration-dependent manner induces proliferation of human and ratBcells and increases insulin secretion by human islets in vitro reverses developmental deformities induced by DYRK1A overexpression in X. laevis embryos
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