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Selleck Chemical LLC CHIR-99021 (CT99021) HCl 5mg 1797989-42-4
Supplier: Selleck Chemical LLC S29245MG
CHIR-99021 (CT99021) HCl is hydrochloride of CHIR-99021, which is a GSK-3?/? inhibitor with IC50 of 10 nM/6.7 nM; CHIR-99021 shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. CHIR-99021 is a potent pharmacological activators of the Wnt/beta-catenin signaling pathway. CHIR-99021 significantly rescues light-induced autophagy and augments GR, ROR? and autophagy-related proteins. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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