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Medchemexpress LLC Chroman 1 dihydrochloride | C24H30Cl2N4O4 | 100 MG
Supplier: Medchemexpress LLC HY15392A100MG
Chroman 1 dihydrochloride is a highly potent and selective ROCK inhibitor. It demonstrates greater potency against ROCK2 than ROCK1, and also inhibits MRCK. This compound has been shown to reduce apoptosis and caspase-3/7 activation in human pluripotent stem cells.
- Highly potent and selective ROCK inhibitor
- More potent against ROCK2 (IC50=1 pM)
- Inhibits ROCK1 (IC50=52 pM)
- Inhibits MRCK (IC50=150 nM)
- Reduces apoptosis in human pluripotent stem cells
- Inhibits caspase-3/7 activation in human pluripotent stem cells
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