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Medchemexpress LLC Chrysin (5,7-Dihydroxyflavone) | 480-40-0 | 99.8% | C15H10O4 | 1 ML
Supplier: Medchemexpress LLC HY1458910MM/1ML
Chrysin is a naturally occurring flavonoid found in passion flowers, honey, and propolis. It is an estrogen blocker intended for research use only and acts as a potential therapeutic and preventive agent against the proliferation and invasion of various human cancer cells. It has shown anti-carcinogenic effects by inhibiting ovarian cancer cell proliferation, inducing cell death through increased reactive oxygen species (ROS) production, elevated cytoplasmic Ca2+ levels, and loss of mitochondrial membrane potential (MMP).
- Activates MAPK and PI3K/AKT pathways
- Suppresses tumor growth by regulating canonical Wnt and nuclear factor NF-κB signaling cascades
- Stimulates phosphorylation of AKT and P70S6K proteins
- Activates phospho-ERK1/2, p38, and JNK proteins within the MAPK pathway in ovarian cancer cells
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