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Cayman Chemical Chrysnthemum LInarIn 50mg

Supplier: Cayman Chemical 2690050 MG

A multi-kinase inhibitor inhibits Axl and c-MET (IC50s 7 and 12 nM respectively) inhibits Axl in 293GT cells expressing Axl and c-MET in NCI H1299 NSCLC cells (IC50s 0 26 and 6 nM respectively) inhibits TYRO3 and MER (IC50s 3 5 and 1 89 nM respectively) induces complete regression of tumors in an Axl/NIH3T3 mouse xenograft model at 0 3 mg/kg induces tumor stasis and regression in an EBC-1 NSCLC mouse xenograft model at 3 and 10 mg/kg respectively reduces tumor growth in an MC38 mouse syngeneic model concomitantly with innate and adaptive immune cell activation
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