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Cayman Chemical ChrysosplentIn 10mg
SDP

Supplier:  Cayman Chemical 3062510 MG

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A peptide fragment of ACTH binds to MCRs (Kis 0 23 14 419 and 4240 nM for MC1R MC3R MC4R and MC5R respectively) an agonist at MC1R that increases adenylate cyclase activity (EC50 3 02 nM in HEK293 cells expressing MC1R) increases MAP following bleeding-induced hypotension in rats 15-30 minutes after i v administration induces melanogenesis in a biphasic manner (EC50s 0 0001 and 0 08 nM) and differentiation of melanocytes at 0 01-1000 nM

Catalog No. 50-299-1401


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