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Medchemexpress LLC Cid44216842 (Cdc42-IN-1) | 1222513-26-9 | 99.8% | 486.38 | 100 MG
Supplier: Medchemexpress LLC HY136379100MG
CID44216842 (Cdc42-IN-1) is a potent and selective guanine nucleotide binding lead inhibitor targeting Cdc42. It demonstrates high efficacy with EC50 values of 1.0 μM for Cdc42 WT and 1.2 μM for Cdc42Q61L mutant in GTP binding assays, and 0.3 μM for Cdc42 WT and 0.5 μM for Cdc42Q61L mutant in GDP binding assays. This compound serves as a valuable molecular probe for research purposes.
- Potent and selective Cdc42 inhibitor
- Effective in both GTP and GDP binding assays
- Specific inhibition with no effects on other GTPases like Rac and Rho
- Suitable for use as a molecular probe in research
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