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Apexbio Technology LLC Cimetidine 51481-61-9 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B15575.1
Cimetidine is an H2 histamine receptor antagonist displaying partial agonist properties at the histamine H2 receptor (H2R) This compound functions by reversibly inhibiting the binding of histamine to gastric parietal cell receptors thereby suppressing gastric acid secretion In cell-based assays cimetidine exhibits an inhibitory activity toward H2 receptors with reported IC50 values in the micromolar range In biomedical research cimetidine is employed to investigate gastric acid secretion regulation mechanisms and receptor-ligand interactions related to gastrointestinal physiology Further due to its pharmacological characteristics distinct from other H2 antagonists cimetidine is frequently studied as an experimental reagent in oncology studies focusing on gastrointestinal tumor growth modulation and related signaling pathways
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