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Medchemexpress LLC Cinnamyl-3,4-dihydroxy-α-cyanocinnamate | 132465-11-3 | 99.41% | 321.33 | 25 MG
Supplier: Medchemexpress LLC 25MGHY138688
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent inhibitor of 12/15-Lipoxygenases (LO) with potential for research into type 1 diabetes mellitus. It has been shown to antagonize the effect of high glucose on protein phosphorylation to mitigate destruction of the endothelial cell barrier in a mouse diabetes mellitus model. In vitro, CDC partially suppressed dextran transport increased by high glucose or 12(S)-HETE.
- Potent inhibitor of 12/15-Lipoxygenases (LO)
- Potential for type 1 diabetes mellitus research
- Antagonizes high glucose effect on protein phosphorylation
- Mitigates endothelial cell barrier destruction in mouse models
- Partially suppresses dextran transport increased by high glucose or 12(S)-HETE
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