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Cayman Chemical cis-10-hydroxy Nortriptyline

Supplier: Cayman Chemical 36659500 UG

A diterpene with diverse biological activities a TRPV3 activator (EC50 16 UM for inducing calcium influx in HEK293 cells expressing TRPV3) inhibits IKBa degradation in TNF-a-stimulated HeLa cells at 60-140 UM reduces amyloid-B (25-35) peptide-induced apoptosis increases in MDA levels and the production of ROS reduces paw edema in a mouse model of hind paw inflammation at 50 mg/kg has anxiolytic and antidepressant-like activity in mice
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