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Cayman Chemical CIsatracurIumbesylate 50mg
SDP

Supplier:  Cayman Chemical 2295950 MG

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A retinoid and an active metabolite of the retinoid etretinate that has antiproliferative activities binds to CRABP-1 and CRABP-II (Kds 3 and 15 nM respectively for the mouse recombinant proteins) but has low affinity for human recombinant retinoic acid receptor-retinoid X receptor (RAR-RXR) heterocomplexes inhibits proliferation (IC50 6 6 UM) and suppresses TNF-a- and IFN-Y-induced protein levels of STAT1 NF- B and RANTES in HaCaT keratinocytes when used at 50 UM inhibits proliferation of HL-60 SCC4 SCC15 and A431 but not MCF-7 cancer cells at 30 UM decreases the severity of psoriatic-like skin lesions in K14-VEGF transgenic mice (20 Ug per mouse)

Catalog No. 50-299-4476


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