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Medchemexpress LLC Cisplatin | 15663-27-1 | 99.3% | 300.05 | 1 G
Supplier: Medchemexpress LLC HY173941G
Cisplatin (CDDP) is an antineoplastic chemotherapy agent that works by cross-linking with DNA and causing DNA damage in cancer cells. It also activates ferroptosis and induces autophagy.
- Works by cross-linking with DNA
- Causes DNA damage in cancer cells
- Activates ferroptosis
- Induces autophagy
- Induces apoptosis in HeLa cells
- Activates the MEK/ERK signaling pathway
- Reduces solid tumor size and weight in melanoma-bearing mice
- Can be used to induce acute kidney injury models
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