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AdipoGen CL 316 243
SDP

Supplier:  AdipoGen AGCR13699M005

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Chemical. CAS 138908-40-4. Formula C20H18ClNO7 . 2Na. MW 419.8 . 46.0. Potent and selective beta3-adrenoceptor agonist EC50=3nM that is >10,000-fold selective over beta1 and beta2. Antidiabetic and antiobesity agent. Causes a rapid decrease in blood glucose level in mice. Increases brown adipose tissue thermogenesis. Induces functionally active mitochondrial uncoupling protein UCP in white fat. Restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice.

Catalog No. 50-256-2204


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