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TARGETMOL CHEMICALS INC CL-AMIDINE HYDROCHLORIDE 10MG

Supplier: TARGETMOL CHEMICALS INC T10831L10MG
Also available in 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50 5.9 uM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro causing cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation. It improves survival in a murine sepsis model. purity: 98%
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