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Cayman Chemical Cl-ncrostatIn-1 10mg
Supplier: Cayman Chemical 1165610 MG
A RIPK1 inhibitor; inhibits RIPK1 activity at 0.3, 3, and 30 µM; inhibits TNF-α-induced necroptosis in FADD-deficient Jurkat cells (EC50 = 180 nM); reduces infarct size when administered i.c.v. pre- and post-occlusion, or post-occlusion only, as 2 µl of a 4 mM solution in a mouse model of MCAO
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