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Medchemexpress LLC Cl2a-sn-38 | 1279680-68-0 | 1480.61 | C73H97N11O22 | 50 MG
Supplier: Medchemexpress LLC HY12894650MG
CL2A-SN-38 is a drug-linker conjugate composed of the DNA topoisomerase I inhibitor SN-38 linked via a hydrolyzable CL2A linker, intended for antibody-drug conjugate (ADC) research and development. It releases active SN-38 within tumor cells and the tumor microenvironment, producing bystander antitumor effects.
- Drug-linker conjugate designed for ADC development.
- Releases SN-38 within tumor cells and tumor microenvironment.
- Camptothecin-class topoisomerase I inhibitor mechanism.
- Molecular formula C73H97N11O22; molecular weight 1480.61.
- Soluble in DMSO (100 mg/mL) and in documented in vivo formulations.
- Store at -20°C under nitrogen; in solution -80°C (6 months) or -20°C (1 month).
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