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Medchemexpress LLC Clarithromycin | 81103-11-9 | 747.95 | 1 ML
Supplier: Medchemexpress LLC HY1750810MM/1ML
Clarithromycin is an inhibitor and agonist with broad-spectrum antimicrobial activity. It inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with an IC50 (Ki) value of 56 (43) μM. Clarithromycin also significantly inhibits the hERG potassium current and affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K.
- Targets bacterial, cytochrome P450, and autophagy.
- Acts as an antibiotic.
- Relevant for research in infection and cancer.
- Inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation.
- Significantly inhibits the hERG potassium current.
- Impairs autophagic flux by affecting the hERG1 and PI3K signaling pathway.
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