Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Clemizole hydrochloride 1163-36-6 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A33165.1
Clemizole hydrochloride is a histamine H1 receptor antagonist reported to inhibit hepatitis C virus (HCV) replication by targeting the viral NS4B protein a component essential for viral RNA replication Clemizole demonstrates antiviral activity in vitro against HCV genotype 2a subgenomic replicons exhibiting an IC50 value around 8 mM When combined with HCV protease inhibitors (such as VX950 or SCH503034) clemizole displays synergistic antiviral effects In contrast additive antiviral effects occur in combination with interferon ribavirin or polymerase inhibitors Clemizole is utilized in research contexts aimed at evaluating its efficacy potential antiviral combinations metabolism pathways and pharmacokinetics relevant to its consideration as a therapeutic candidate for HCV infection
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?