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TARGETMOL CHEMICALS INC CLEVUDINE 25MG
Supplier: TARGETMOL CHEMICALS INC T644625MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly clevudine is phosphorylated to its active metabolites clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA) therefore the patient is less likely to have a relapse after treatment is discontinued. purity: 99%
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